Process consolidating memories dating personal hiv
He states that “retrograde amnesia gradients do not reveal time courses of memory processes.” In summary, I believe that ambiguities about how we in the field define the posttraining consolidation process reflect, in large part, the different results and conclusions emerging from studies that used different amnestic treatments.Despite the semantic debate about consolidation and reconsolidation, several studies of the last few years have demonstrated that reconsolidation only partially recapitulates the anatomical, pharmacological, and molecular substrates of consolidation [-consolidation, and, it is now generally accepted that the term reconsolidation is used not to mean faithful repetition of the initial posttraining consolidation, but rather the functional outcome of the process, which is to make memory stable again.] has been challenged.Disrupting events include brain trauma, seizure, electroconvulsive shock (ECS), brain cooling, new learning, and the administration of drugs such as inhibitors of protein and RNA synthesis.
The process by which a labile memory again becomes stable and therefore insensitive to disruption has been termed , reminiscent of the labile phase of the posttraining consolidation process.(5) Functions of memory reconsolidation; (6) Disrupting reconsolidation: an impairment of memory stabilization or retrieval? Studies of verbal learning and trauma-induced retrograde amnesia in humans that began more than 100 years ago lead to the idea that memories become long-lasting through a process of “consolidation” .Over the last century, this process has been extensively investigated behaviorally, pharmacologically, and molecularly in many species, including humans.The findings that stabilized memories can become labile have challenged the classical view of how memories are consolidated over time and stored.On the other hand, the reconsolidation process is not fully understood, and theories about the nature and function of memory reconsolidation remain controversial.
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Memory formation is a complex and very dynamic process.